TikTok Influencer Marketing AgencyA division of Influencer Advisory

How do dietary supplements sell on TikTok Shop?

The ones that sell most have thousands of creators selling them. 41 supplement and health shops made FastMoss's September 2026 ranking, and the ten that sold the most each had more than 10,000 creators linked to them.

The 10 that sold most in September 2026

ShopSeptember salesChange on AugustCreators linked
Micro Ingredients$6.16 milliondown 5.0%53,573
Toplux Nutrition$4.34 milliondown 4.6%14,550
MaryRuth's$3.37 milliondown 11.2%42,462
Bella All Natural$2.66 millionup 39.9%57,143
Physician's Choice$2.49 millionup 4.2%21,766
Leefar US$2.45 millionup 16.7%17,408
O Positiv$2.43 millionup 17.9%35,523
Cata-Kor USA$2.04 millionup 2.3%10,372
Lemme$1.95 milliondown 6.2%20,191
NeoCell Collagen$1.93 milliondown 17.2%17,807

Source: Our own count of FastMoss's September 2026 US shop rankings, Health category

  • All 41 together sold $55.3 million in September. 23 grew on August and 18 shrank.
  • The five that fell hardest, down 56% to 84%, each had fewer than 4,000 creators linked.
  • Milamiamor's 15 Day Cleanse had sold 1.4 million units by May 2024, FastMoss reported. In September 2026 the shop sold $114,102, down 72% on August.

Source: FastMoss, health supplements on TikTok, May 2024

What O Positiv's founder sees

O Positiv joined TikTok in October 2023, one of the first brands on it, its co-founder says. In September it was up 17.9%.

“If you look at the top health brands on TikTok Shop, they're the top health brands in general, right? They're the top health brands on Amazon, they're the top health brands in retail because there's this halo that comes from TikTok that I haven't seen since the early days of Meta.”
Bobby Bittonco-founder and CEO of O Positiv

Fitt Insider, August 2026

What TikTok lets you sell

  • Supplements are a restricted category. You complete TikTok's category qualification before you list, and listing without approval breaks TikTok Shop's policies.

Source: TikTok Shop Seller University, Requirements for Responsible Health-Related Content

  • Products and supplements that claim to aid weight management or fat reduction are on TikTok's prohibited list. So is a product with GLP-1 in its title or branding, unless it's clearly sold as support for people already on GLP-1 medication.

Source: TikTok Shop Seller University, Prohibited Products Policy

What a creator says about your product counts as much as what you say, and a commission on every sale pushes them to say more.

“Then toss in potential creator commissions from TikTok Shop supplement category sales and those loud praises for products or ingredients in some cases come way too close to the line of making disease treatment claims.”
Joshua Schallhost of a show on the supplement business

His YouTube show, March 2024

Get my free TikTok Shop audit

We find the creators already selling products like yours on TikTok Shop, bring them into a private creator community and coach them, then put ads behind the videos that sell.